Lorelei, he’s on a hot search？ What happened to the ＂life-saving medicine＂ of ＂allergic star people＂
Source: Jiangsu CDC (jscdcwx)
Spring has come, and "allergic star people" are getting worse.
Some people say, chlorine ray is in his hand, don’t panic!
However …
How did this get on the hot search?
The antihistamine represented by loratadine is a "life-saving medicine" for many allergic people.
So, many people rely on antihistamines for a long time, will there be side effects? What are the precautions?
Who is the "life-saving medicine" chlorine ray?
Loratadine is a commonly used drug to relieve allergic symptoms and one of the representative drugs of antihistamines.
In April and May every year, willow flocks are high, and many people will take loratadine with them in order to relieve allergic symptoms.
Although it is often used, many people don’t know how it works.
This is going to start with "what is the allergy?"
Generally speaking, allergy means that the immune system overreacts and misjudges substances from outside as "harmful substances".
At this time, the immune system will release a substance called "histamine", which will combine with histamine receptors in the body.
Therefore, patients will have respiratory tract, eyes, skin and other symptoms at the same time or successively.
H1 antihistamines represented by loratadine and cetirizine, as the name implies, are drugs that can prevent histamine from binding to its receptor, so that histamine cannot play its role.
Therefore, after taking antihistamines, symptoms such as itchy skin and sneezing will be quickly relieved. Therefore, antihistamines are called "life-saving drugs" by many allergic people.
Can this medicine be taken for a long time?
Some people regard loratadine as a "life-saving artifact all year round". But are there any side effects from long-term use of antihistamines?
In fact, loratadine can not eradicate allergens, and long-term use may lead to some adverse reactions.
side effect
First-generation antihistamines (such as diphenhydramine and bromophenamine) can cause adverse reactions such as drowsiness, fatigue and dizziness. It has anticholinergic effect, which may cause blurred vision, dry eyes, nose and mouth, urinary retention, constipation, etc. The elderly and children should use it with caution.
The second generation antihistamines (such as loratadine and cetirizine) have weak sedative effect, are not easy to cause drowsiness, and have high safety; There is no obvious anticholinergic adverse reaction, so it has no antitussive function.
Third-generation antihistamines (such as levocetirizine hydrochloride and desloratadine) have relatively strong antiallergic effect and relatively few side effects, and some drugs can be used for pregnant and lactating women and children.
Therefore, if you need to take such drugs for a long time, it is recommended to consult a doctor. The following is a summary of medication for reference.
1. Choose drugs carefully
Antihistamines are only suitable for use under the guidance of a doctor to relieve the symptoms caused by allergic diseases. Pregnant and lactating women, as well as the elderly and children, should be cautious when using drugs.
2. Pay attention to the time and dosage of medication.
Even loratadine and cetirizine, which are considered very safe in clinic, should not be taken continuously for more than one month. Because of the individual differences in medication, if the symptoms are not improved, the dosage of the drug should not be increased without authorization, and other drugs or treatment methods should be selected under the guidance of a doctor.
Step 3 don’t drink
Do not drink alcohol while taking antihistamines, otherwise it will increase the burden on the liver and inhibit the central nervous system.
4. Don’t take it before skin test.
Loratadine can prevent or reduce the positive reaction of skin test and affect the results.
5. Beware of the "chain reaction" of drugs
Antifungal drugs and macrolide antibiotics can increase the content of loratadine in blood, and it is easy to aggravate the adverse reactions when combined with antihistamines.
6. Patients with heart disease should pay attention to it
In the case of rational drug use, antihistamines have very little hepatorenal toxicity, but literature shows that some first-generation and second-generation antihistamines may have potential cardiotoxicity. Although rare, people who have heart disease or cardiovascular risk should pay attention when using antihistamines for a long time.
What else can I do to deal with allergies?
In addition to using antihistamines, many "senior patients" said that the best way to deal with it is to wear a mask! Wear long sleeves!
"Allergic star people" can do the following things in their daily life.
1. Protect yourself when going out: Wear a mask, and you can wear a thin coat for fear of allergies in bare arms. When going out, the clothes are inevitably stained with allergens such as pollen and dust outside. I suggest you wash your hair, take a shower and change your clothes when you get home.
2. Clean the nasal cavity every day: people with allergic rhinitis or sensitive to pollen and catkins should clean the nasal cavity with normal saline 2-3 times a day.
3. Do a good job in indoor cleaning: Usually, you can use high-temperature steam cleaning products or mite removal instruments to wash sheets, quilt covers and pillowcases more often.
4. Regular physical exercise: Moderate exercise will stimulate the improvement of immunity, but if the exercise load is too large, it will also reduce immunity, so physical exercise must be gradual, persistent and adequate.
There are always a few allergic people around everyone. Hurry up and forward it to someone you care about ~
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Reference sources: People’s Daily Popular Science, Popular Science China, etc.
-Produced by the editorial department of "I wish you health" of Jiangsu Phoenix Science and Technology Publishing House-
Content planning/typesetting: Zhu Jingjing, Gu Xinyu
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